Antiemetics

Domperidone 10 mg, №30

International Nonproprietary Name (INN): Domperidone

Pharmaceutic group: Antiemetic

Presentation:

Tablets 10 mg n30.

Available with prescription

Question?

THERE ARE CONTRAINDICATIONS. CAREFULLY READ THE INSTRUCTIONS FOR USE, OR OBTAIN A SPECIALIST ADVICE

Domperidone blocks the action of dopamine. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which, among others, regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa).

Domperidone helps to relieve stomach discomfort, nausea, vomiting and reflux. It also relieves uncomfortable sensations of fullness. It works by increasing the action of the muscles in the gastrointestinal tract so that food moves more effectively through the digestive system. Domperidone is used in conditions caused by food staying in one place for too long or by stomach contents flowing the wrong way along the gastrointestinal tract.

Domperidone is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

•are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine;

•have a prolactinoma;

•have gastrointestinal problems which would be affected by the stimulation of gastrointestinalmuscles;

•have kidney problems;

•have liver problems.

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child under 12 years of age or who weighs less than 15 kg.

Over time it is possible that Domperidone can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Domperidone has become unsuitable, it is important that the prescriber is contacted immediately.